1x PCIe 5.0 x16 slot for graphics card 1x PCIe 5.0 x4 slot for M.2 SSD
If the PCIe 5.0 x4 M.2 slot is occupied, the lanes of the graphics card slot are halved to x8 and thus the max. throughput - also that of a PCIe 4.0 graphics card. So if possible, use all other M.2 slots first, unless you have a PCIe 5.0 SSD and want to make use of the full performance - at the expense of graphics performance. With PCIe 5.0 graphics cards, x8 should initially be less of a problem (equivalent to PCIe 4.0 x16).