The function and regulation of chick Ebf genes in somite development

The book "The function and regulation of chick Ebf genes in somite development" provides a comprehensive investigation into the role of Ebf genes (Early B-cell Factor) in the development of somites, which serve as precursors to the axial skeleton. The Ebf genes are members of the EBF helix-loop-helix transcription factors and are known for their functions in the differentiation of B lymphocytes and neural cells. This work details the expression and regulation of Ebf genes in the somites, particularly highlighting interactions with BMP4 and Shh. The results show that cEbf1 plays a key role in sclerotomal development and can induce the expression of other sclerotomal markers. These findings contribute to the understanding of the complex genetic networks that govern somatic development.