Pharmacology of Neurotransmitter Release

The book "Pharmacology of Neurotransmitter Release" offers a comprehensive analysis of the molecular mechanisms underlying the exocytosis of neurotransmitters. It highlights the role of presynaptic calcium channels and the core proteins of the secretory machinery, as well as the effects of clostridial toxins and α-latrotoxin, which are crucial for understanding exocytosis. Furthermore, it examines the regulation of neurotransmitter release by presynaptic receptors for endogenous chemical signals. These receptors, including ligand-gated ion channels and G-protein-coupled receptors, play a central role in fine-tuning the release process. The therapeutic possibilities arising from the modulation of these receptors are also discussed in detail. With 582 pages, the book provides a detailed and well-founded perspective on the pharmacology of neurotransmitter release, making it a valuable resource for professionals and students in the fields of neuroscience and pharmacology.