Novel Methods For Pyrrole Synthesis

"Novel methods for pyrrole synthesis" is a specialized book that focuses on the synthesis of functionalized pyrroles, which are of great interest in heterocyclic chemistry. These compounds are characterized by their diverse bioactive properties and are used in various natural products, including porphyrins. The book provides a comprehensive overview of novel approaches to the synthesis of substituted pyrroles and their application in the total synthesis of marine anticancer agents such as Lamellarin O, Lamellarin Q, Lukianol A, and Rigidin. A significant part of the work deals with the synthesis of ketene N,S-acetals and their conversion into functionalized pyrroles. Additionally, methods for the partial or complete sulfhydrolysis of dithioacetals to thiol esters or aldehydes are discussed. The book also includes a thorough overview of the methods for pyrrole synthesis, summarized in a separate chapter. With detailed experimental procedures and original spectra, it offers valuable information for advanced students as well as professionals in the industry who are involved in the development of anticancer agents.