Mycobacterium Tuberculosis

The book "Mycobacterium Tuberculosis" by Olajide Mustapha provides a comprehensive analysis of tuberculosis (TB) and its resurgence as a significant health issue, particularly in the context of the AIDS epidemic and the emergence of multidrug-resistant (MDR TB) and extensively drug-resistant (XDR TB) strains. It highlights the role of enzymes involved in the biosynthesis of the mycobacterial cell wall and emphasizes UDP-galactopyranose mutase (UDP-Galp mutase) as a key target for the development of new drugs. The book is aimed at chemists and professionals in the field of tuberculosis and offers detailed methods for synthesizing inhibitors that target these enzymes. By combining chemical synthesis methods with structural analyses, it makes a valuable contribution to the research and development of new therapeutic approaches to combat tuberculosis.