Molekulare Virologie

This established standard work provides a balanced overview of known human and animal pathogenic viruses, such as papillomaviruses and influenza viruses, and has been supplemented with more recently emerged viruses, particularly the Zika virus, the novel coronavirus SARS-CoV-2, and the Schmallenberg virus, a bunyavirus that infects cattle, sheep, and goats. The first part of the book presents the general principles of the structure, replication, and life cycles of viruses and describes the main pathogenic and immunological mechanisms of viral diseases. It also covers diagnostics and therapy, as well as the epidemiology of such infections and the current repertoire of methods used by virologists. The second, specialized part systematically explores the diversity of human and animal pathogenic viruses. Detailed descriptions are provided for the morphology, genome organization, protein composition, and replication mechanisms of various virus families. For the most important representatives, the authors offer an overview of the relevant clinical aspects in human medicine and veterinary medicine. Legal questions regarding epidemics are also addressed. This textbook has served for many years as a reliable introduction to the molecular and cellular biology foundations of virology and is indispensable for professionals and students alike. The 4th edition has been updated with current data on the respective viruses, providing an up-to-date overview of replication strategies and linking them to the pathogenesis of the pathogens. It includes virus species that have emerged in recent years and have dominated public discussion in many respects. Not least among these are human infections with the novel coronavirus SARS-CoV-2, the Zika virus, both animal and human pathogenic bornaviruses, and the Schmallenberg virus.