Influenza Impfstoffproduktion mit adhärenten Vero Zellen

Influenza vaccine production with mammalian cells represents a possible process for the production of vaccines on an industrial scale, which could serve to improve the prevention of an imminent pandemic. This book describes the establishment of a process for influenza virus production using adherent Vero cells. The author Christian Dietzsch gives an introduction about Vero cells, influenza virus and possible manufacturing processes with different reactor systems. Experimental results concerning cell growth and virus production in static and microcarrier cell culture systems are presented. The influence of different parameters (Multiplicity of Infection, trypsin concentration) on the infection of cell cultures in different media (serum-containing/serum-free) is described. This book is aimed at students of biotechnology as well as.