Frühe Traumata als Ursprung von chronischer Entzündung

The aim of the book is to raise awareness among doctors and researchers about the significant long-term health effects of early, persistent, and severe trauma. The author, an internist, rheumatologist, and fundamental researcher in psychoneuroimmunology, illustrates the connections between adverse childhood experiences and typical follow-up problems in adults. Following early traumatic experiences and childhood stress, there is a higher incidence of mental illnesses, chronic pain, sleep disorders, dental issues, obesity, cardiovascular diseases, asthma, diabetes mellitus, and chronic inflammation. A selection of diseases clearly demonstrates the long-term consequences of early childhood trauma. These childhood experiences create a kind of long-term programming that negatively impacts adulthood. From his psychoneuroimmunological perspective, Rainer Straub identifies four factors that link the brain to the immune system and contribute to chronic immune activation: direct connectors originating from the brain, indirect connectors that operate through hormonal and neural pathways, extracorporeal factors – the environmental influences – and pleiotropic connectors – the gene variants.