End-zu-End- vs. End-zu-Seit-Anastomose

The study "End-to-end versus end-to-side anastomosis" of the Institute of Neuroanatomy of the Hannover Medical School in cooperation with Prof. Dr. med. Dr. h.c. mult. Madjid Samii (International Neuroscience Institute Hannover) compares the innovative surgical technique "end-to-end anastomosis" to restore severed nerves with the classical neurosurgical procedure "end-to-end anastomosis" in the established Ischiadicus model of the rat. The methodological evaluation was performed by histomorphometric analyses, histological and immunohistochemical techniques, electrophysiological measurements and the use of tracer dyes for retrograde neuron marking. After eight weeks, the regeneration results for both methods were compared with each other as well as with non-operated nerves of healthy animals. In addition, the erge.