Creatine and Creatine Kinase in Health and Disease

Gajja S. Salomons, Markus Wyss, 2010
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The book "Creatine and Creatine Kinase in Health and Disease" offers a comprehensive analysis of the role of creatine and creatine kinase in human health. Although creatine was discovered in the 1830s, the understanding of its significance for well-being has expanded significantly in recent years. The authors illuminate the various positive effects of creatine, ranging from neuroprotective properties to potential benefits in the treatment of neurodegenerative diseases. Special attention is given to the interaction between creatine and creatine kinase and their influence on brain function. Additionally, the genetic disorders of creatine biosynthesis and transport that can lead to cognitive impairments are discussed in detail. The book also examines the effects of creatine on muscle growth and strength, as well as the safety of oral creatine supplementation. Finally, innovative approaches in systems biology are presented, which deepen the understanding of the diverse effects of creatine and creatine kinase and highlight future research directions.

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