Bioreactor Processes Based on Disposable Materials

The book "Bioreactor Processes Based on Disposable Materials" by Matthieu Stettler offers a comprehensive analysis of industrial cell culture technology focused on the production of therapeutic proteins. These proteins are crucial for the treatment of infectious diseases, cancer, and autoimmune disorders. In today's world, it is essential to minimize the time and costs from the discovery of a molecule to full-scale production. The work highlights innovative concepts based on disposable materials, which are considered promising alternatives to traditional bioprocess equipment. The dissertation examines the development of such disposable systems in the application of mammalian cell culture and demonstrates their advantages in terms of cost-effectiveness, user-friendliness, and flexibility. Notably, it emphasizes the application of orbital shaking technology, suitable for a range of operational scales, from a few milliliters for optimization purposes to production scale.