Antibiotika: Ein Überblick über die Geschichte, den Wirkmechanismus und das Medikament

Most of the antibiotics currently in use were discovered more or less by chance, and their mechanisms of action were only elucidated after their discovery. To meet the medical need for next-generation antibiotics, a more rational approach to antibiotic development is clearly required. This book begins with a general introduction to the history of antimicrobial agents, their mechanisms of action, and the problem of antibiotic resistance, and then provides a comprehensive overview of the currently known classes of antibiotics, their mechanisms of action, and the target structures they affect. Additionally, it includes the latest information on the molecular mechanisms of current blockbuster antibiotics. With its thorough overview of the current and future development of antibacterial agents, this book is essential reading for anyone involved in the development and therapeutic application of novel antibiotics.