A practical Introduction and Application of L-glutamine-(asparagin)ase

The book "A Practical Introduction and Application of L-glutamine-(asparagin)ase" offers a comprehensive introduction to the role of the enzyme L-glutamine-(asparagin)ase, which is responsible for the hydrolysis of L-asparagine and L-glutamine. It discusses the biochemical processes associated with the activity of this enzyme and highlights its applications in industry as well as in clinical therapy. In particular, the significance of the enzyme in the treatment of acute lymphoblastic leukemia is emphasized, where the reduction of asparagine and glutamine through specific enzymes is a common therapy. Additionally, it addresses the potential risks of supplementing with these amino acids, which can lead to more aggressive tumor development. The book is aimed at professionals and students who wish to gain a deeper understanding of the biochemical mechanisms and practical applications of L-glutamine-(asparagin)ase.