Yup, the V2 will let you store 2 profiles on the device so that you can take it with either of those to play with at another location on a different PC and not need Razer Synapse for it to remember your settings. Using Razer Synapse allows you to swap between a huge numbers of profiles. I've splashed out on the Azeron Cyborg, so if you want you can buy my V2....
The hand rest is not flat, it is curved. I see two problems, not really comfortable (more pressure in the palm under little finger) and it is hard to reach the top buttons with the little finger.
Yes, only with a keyboard/mouse adapter. There are 2 models; XIM 4 and XIM Apex. But hard to get and again need to be configured with an Android or iOs app.