I have been using this for 30 years on MX, MTB, and cars. If you have a bolt/screw that gets a lot of vibration and your life depends on it, then you are mad if you don't use Loctite. Easy to apply, tighten, and loosen.
For nuts and bolts that you regularly remove or adjust, such as wheel nuts, it gets messy and a bit too much trouble. Then you are better off using grease and ensuring that it is tightened correctly. But for everything else, especially brakes, Loctite is your best friend.…plus